Microsatellites

SNPs

1. Map the genomic distribution of the following two marker sets.

TPOX

rs10012227

rs10012227 OR rs10127540 OR rs10141763 OR rs1024116 OR rs10843344 OR rs12402499 OR rs12498138 OR rs12913832

Which two microsatellites are closest together ?

D2S1338

rs10127540

D12S391

rs10141763

2. A colleague has said the last three exons of tyrosinase (TYR) are duplicated as a pseudogene.

VWA

rs1024116

how would you quickly test this suggestion ? - is it true ?

Snpper

rs10843344

In silico PCR

rs12402499

3. How many promotor SNPs are there in IL10 ?

rs12498138

rs12913832

4. What is the rs-number of OCA2 Arg163Gln ?

rs1321333

rs1335873

rs1409842

5. Use as many databases as possible to answer the following query:

rs1426654

Do South Americans show a toxic response to alcohol ?

rs1498444

Hint: you will need to check ALFRED

ALFRED

rs1573020

PubMed

rs16891982

Snpper

rs16968965

OMIM

rs1701930

SNPedia

rs17130385

Wikipedia

rs17287498

rs17403380

rs17742080

rs182549

rs1834619

rs1863086

rs1886510

rs1978806

rs2026721

rs2040411

rs2051827

rs2065160

rs2065982

rs2303798

rs2304925

rs239031

rs2471552

rs252155

rs2572307

rs2814778

rs3027749

rs3217863

rs3785181

rs379839

rs3814614

rs4540055

rs4780476

rs4792928

rs4937417

rs4979274

rs5030240

rs509360

rs5997008

rs6880706

rs6993205

rs7158003

rs722098

rs727811

rs730570

rs773658

rs7897550

rs8137373

rs881929

rs896788

rs917118

rs9916327